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Medchemexpress LLC Benzoic acid, 4-[6-(2-chloro-6-cyclopropylbenzoyl)imidazo[1,5-a]pyrimidin-8-yl]-2-hydroxy- | 1677668-27-7 | 98.0% | 433.84 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1977510MM/1ML

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GNE-6468 is a highly potent and selective RORγ (RORc) inverse agonist with an EC50 value of 13 nM for HEK-293 cells and 30 nM for IL-17 PBMC. It is intended for research use only.

  • Highly potent and selective RORγ (RORc) inverse agonist.
  • Exhibits anti-inflammatory activity in human PBMC by inhibiting IL-17 production.
  • Displays high predicted clearance values in human and rodent hepatocytes.

Catalog No. 50-004-02029


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