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Medchemexpress LLC Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]- | 54-31-9 | 99.8% | 5 G

Supplier: Medchemexpress LLC HYB01355G
Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. It also acts as a GABAA receptor antagonist, displaying 100-fold selectivity for α6-containing receptors over α1-containing receptors. It functions as a loop diuretic and is used in studies of congestive heart failure, hypertension, and edema.
- Potent and orally active inhibitor of NKCC cotransporter
- Antagonist of GABAA receptors with high selectivity for α6-containing receptors
- Functions as a loop diuretic
- Used for the study of congestive heart failure, hypertension, and edema
- Targets NKCC and GABA receptor
- Pathway involves membrane transporter/ion channel and neuronal signaling
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