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Medchemexpress LLC Berberine chloride hydrate | 68030-18-2 | 99.8% | 389.83 | 1 ML

Supplier: Medchemexpress LLC HY1757710MM/1ML
Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. It induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase, and possesses antineoplastic properties. It also has antineoplastic properties.
- Has potential inhibitory effects on the proliferation of four colorectal carcinoma cell lines LoVo, HCT116, SW480, and HT-29.
- Induces a time- and dose-dependent inhibition of LoVo cell growth.
- Exposure leads to accumulation of LoVo cells in the G2/M phase.
- Suppresses cyclin B1, cdc2, and cdc25c protein expression.
- Inhibits the growth of human colorectal adenocarcinoma in vivo.
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