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Medchemexpress LLC Berberine (hemisulfate) | 316-41-6 | 384.40 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN0716A
Berberine hemisulfate, also known as Natural Yellow 18 hemisulfate, is an alkaloid derived from the traditional Chinese herbal medicine Huanglian. This compound is the hemisulfate form of Berberine.
- Exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity.
- Shows antimicrobial activity through inhibition of cell division protein FtsZ, or through DNA/RNA binding and subsequent DNA/RNA damage.
- Exhibits anti-inflammatory activity by inhibiting TNF-α and the activation of its downstream pathway AP-1 and NF-κB.
- Demonstrates neuroprotective efficacy by inhibiting reactive oxygen species (ROS) production and caspase activation, and activating the PI3K/Akt signaling pathway and heme oxygenase-1 (HO-1) expression.
- Attenuates metabolic diseases through regulations of lipid composition and inhibition of insulin resistance.
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