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Apexbio Technology LLC Berberine hydrochloride 633-65-8 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC N16995.1
Berberine hydrochloride (CAS 633-65-8) is a bioactive alkaloid designed to modulate glucose metabolism and related pathways Berberine hydrochloride exerts its biological activity primarily by inhibiting mitochondrial oxidative phosphorylation which promotes glycolysis and by functioning as an -glucosidase inhibitor thereby impeding disaccharidase activity and limiting intestinal glucose absorption In animal models with diet-induced obesity and clinical studies in type 2 diabetes patients berberine hydrochloride demonstrates enhanced glucose uptake increased glucose consumption under insulin-deficient conditions and improved insulin sensitivity No IC50 value has been reported Based on these pharmacological properties berberine hydrochloride holds research potential in diabetes and metabolic disorder applications
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