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Cayman Chemical Bergamottin Natural Products E

Supplier: Cayman Chemical 1000943910 MG
A naturally occurring furanocoumarin; inhibits migration and invasion of HT-1080 fibrosarcoma cells at sub-cytotoxic concentrations via inhibition of MMP-9 expression; shows antiproliferative activity against HepG2 liver, HL-60 leukemia, and BGC-823 gastric cancer cell lines in a dose-dependent manner; induces cell death of CHO cells following near ultraviolet irradiation; inhibits CYP3A4 (Ki = 7.7 μM); a mixed inhibitor of simvastatin drug metabolism (Ki = 174 μM); increases glucose consumption in HepG2 cells in a dose-dependent manner
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