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Apexbio Technology LLC Bestatin 58970-76-6 25mg
Supplier: Apexbio Technology LLC A257525
Bestatin (Ubenimex) is an inhibitor targeting aminopeptidase B and leucine aminopeptidase enzymes without inhibitory activity against aminopeptidase A trypsin chymotrypsin elastase or pepsin It exerts its inhibitory effect through chelation of metal ions by the adjacent amino and hydroxyl functional groups and this inhibition cannot be reversed by zinc supplementation Bestatin is employed in biochemical research to investigate protein degradation pathways enzyme specificity and aminopeptidase roles in biological processes and disease models It shows no detectable antibacterial or antifungal activity at concentrations around 100 pg/ml The reported IC50 values against aminopeptidase B and leucine aminopeptidase are in the nanomolar range
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