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Medchemexpress LLC Betahistine (dihydrochloride) | 5579-84-0 | 99.8% | 1 ML
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Supplier:  Medchemexpress LLC HYB0524A10MM/1ML

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Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. It is used for the study of rheumatoid arthritis (RA).

  • Orally active histamine H1 receptor agonist and H3 receptor antagonist.
  • Used for the study of rheumatoid arthritis (RA).
  • Inhibits [125I]iodoproxyfan binding to H3 receptors.
  • Regulates cAMP formation in CHO cells expressing H3 receptors, showing both inverse agonism at low concentrations and agonism at higher concentrations.
  • Increases tele-methylhistamine (t-MeHA) levels in mice.
  • Attenuates murine collagen-induced arthritis by suppressing inflammatory and Th17 cell responses.

Catalog No. 50-004-06873


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