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Medchemexpress LLC Bezuclastinib | 1616385-51-3 | 98.8% | C19H17N5O | 1 MG

Supplier: Medchemexpress LLC HY1455571MG
Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor that demonstrates potent activity against KIT D816V. It is used in the research of nonadvanced systemic mastocytosis (NonAdvSM).
- Orally active and highly selective tyrosine kinase inhibitor
- Potent activity against KIT D816V
- Used in research of nonadvanced systemic mastocytosis (NonAdvSM)
- Appears as a white to off-white solid
- Shows high selectivity to KIT D816V
- Minimal brain penetrance
- IC50 of <1 μM against c-Kit and c-kit D816V
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