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Medchemexpress LLC BHPI | 56632-39-4 | 98.0% | 50 MG
Supplier: Medchemexpress LLC HY1282550MG
BHPI is an inhibitor of the nuclear receptor ERα, which also activates PLCγ and UPR. It exhibits antitumor activity against breast, endometrial, and ovarian cancers. BHPI completely inhibits the proliferation of ERα-positive breast, endometrial, and ovarian cancer cells. It also inhibits tumor growth and leads to rapid regression in mouse xenograft models using MCF-7 tumors.
- Inhibits nuclear receptor ERα
- Activates PLCγ and UPR
- Exhibits antitumor activity against breast, endometrial, and ovarian cancers
- Completely inhibits proliferation of ERα-positive cancer cells
- Inhibits cell proliferation in two-dimensional adherent cultures
- Inhibits tumor growth in mouse xenograft models
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