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Medchemexpress LLC BI-0115 | 4929-23-1 | 99.7% | 287.74 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY23999100MG

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BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 μM) that blocks cellular uptake of oxLDL. Its binding triggers receptor inhibition by forming dimers of the homodimeric ligand binding domain. It is for research use only.

  • Designed by Boehringer Ingelheim and available free of charge through opnMe.com, associated with its negative control.
  • Efficiently reduces oxLDL internalization in the cellular context.
  • IC50 values of the cellular assay (5.4 μM) are in good agreement with determined Kd values in SPR (4.3 μM) and ITC (6.99 μM).

Catalog No. 50-004-01215


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