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Medchemexpress LLC BI-3802 | 2166387-65-9 | 99.3% | 484.98 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1087051MG

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BI-3802 is a chemical probe and a highly potent BCL6 degrader. It inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. This compound induces the polymerization of BCL6 and promotes BCL6 degradation, which is dependent on the E3 ligase SIAH1. BI-3802 exhibits antitumor activity. It was designed by Boehringer Ingelheim and can be obtained free of charge through their open innovation portal opnMe.com, along with its negative control.

  • Highly potent BCL6 degrader.
  • Inhibits the BTB domain of BCL6 with an IC50 of ≤3 nM.
  • Induces polymerization of BCL6.
  • Promotes BCL6 degradation dependent on E3 ligase SIAH1.
  • Demonstrates antitumor activity.
  • Available as a chemical probe.

Catalog No. 50-003-44654


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