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Medchemexpress LLC BI-4020 | 2664214-60-0 | 98.82% | 50 MG
Supplier: Medchemexpress LLC HY12955050MG
BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It exhibits high kinome selectivity and favorable DMPK properties. This compound is stable under recommended storage conditions.
- Inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines).
- Inhibits the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM).
- Shows activity against EGFR wt (IC50=190 nM).
- For research use only by suitably qualified experienced scientists.
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