Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC BI605906 | 960293-88-3 | 99.7% | 1 ML
Supplier: Medchemexpress LLC HY1301910MM/1ML
BI605906 is a chemical probe and a novel IKKβ inhibitor, demonstrating improved selectivity. It inhibits IKKβ with an IC50 value of 380 nM when assayed at 0.1 mM ATP and is intended for research use only.
- Targets IKKβ as a selective inhibitor.
- Inhibits IKKβ with an IC50 value of 380 nM at 0.1 mM ATP.
- Shows high selectivity among over 100 tested protein kinases.
- Partially inhibits IL-1-stimulated activation of IKKε/TBK1.
- Suppresses TNFα-induced degradation of NF-KB negative regulator IκB in primary mouse hepatocytes.
- Strongly inhibits TNF-α-dependent expression of various inflammatory mediators.
- Does not suppress mTOR signaling or activate AMPK.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?