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Medchemexpress LLC Bicuculline (methochloride) | 38641-83-7 | 99.8% | 417.84 | 50 MG
Supplier: Medchemexpress LLC HY13779050MG
Bicuculline methochloride is a selective GABAA receptor antagonist with an IC50 value of 3 μM. It induces clonic tonic convulsions in mammals and blocks Ca2+ activated potassium channels, making it useful in studies of epilepsy and related psychiatric disorders.
- Selective GABAA receptor antagonist (IC50 3 μM)
- Induces clonic tonic convulsions in mammals
- Blocks Ca2+ activated potassium channels (SK1 and SK2)
- Used in epilepsy and related psychiatric disorder research
- Creates animal epilepsy models by inhibiting inhibitory neurotransmission
- Increases capillary blood flow in the epileptic focus
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