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Apexbio Technology LLC Bilobalide 33570-04-6 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC A32415.1

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Bilobalide (CAS 33570-04-6) is a terpenic trilactone derived from Ginkgo biloba noted for neuroprotective activities It modulates neuronal function partly via interactions with ion channel receptors as evidenced by altered potencies upon receptor-site mutations Bilobalide promotes -secretase-mediated cleavage of amyloid precursor protein (APP) resulting in increased sAPP secretion and reduced amyloid-beta (A ) levels through a PI3K-dependent signaling pathway Animal studies indicate analgesic activity reducing hyperalgesia and inflammation-induced edema comparable to diclofenac Additionally bilobalide improves cognitive performance in animal models associated with enhanced antioxidant markers (SOD/GSH) and reduced oxidative stress (NOS/MDA)

Catalog No. 50-000-63601


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