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Chemie Tek BINIMETINIB MEK162 50MG
SDP

Supplier:  Chemie Tek CTA16250MG

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ARRY-162 is a potent, orally bioavailable and non-ATP competitive inhibitor of MEK1/2 (IC50 = 12 nM ) and cellular pERK (IC50 = 11 nM), selective against a panel of other 220 kinases (has no activity at 10 uM). It shows ex vivo inhibition of cytokine production such as IL-1, TNF and IL-6. It is currently in clinical trials.

Catalog No. NC0792194


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