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Cayman Chemical BIO1211trIfluoroACTAte sa 10mg
Supplier: Cayman Chemical 3500710 MG
A peptide inhibitor of α4β1 integrin (IC50 = 0.004 µM); selective for α4β1 integrin over α4β7 (IC50 = 2 µM), as well as α1β1, α5β1, α6β1, αLβ2, and αIIBβ3 (IC50s = >100 µM for all); binds to α4β1 (IC50 = 1 nM); inhibits Jurkat cell adhesion (IC50 = 4 nM); prevents carbachol-induced airway hyperresponsiveness in an ovine model of allergy-induced asthma at 3 mg/animal inhaled
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