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Sigma Aldrich Fine Chemicals Biosciences BioTracker Far red Labile
Supplier: Sigma Aldrich Fine Chemicals Biosciences SCT037
Iron the most abundant transition metal in our bodies is involved in a number of biologically important processes such as respiration oxygen transport and energy production in collaboration with oxygen. In living cells iron exists mainly as ferrous (Fe2) and ferric (Fe3) ionic forms. As a major contributor to oxidative damage of cells Fe2 is implicated in serious diseases such as cancers and neurodegenerative disorders because of its ability to produce harmful reactive oxygen species via contact with oxygen superoxide and hydrogen peroxide (H2O2).BioTracker far-red labile Fe2 dye is a fluorescent probe that specifically detects labile iron (II) ions (Fe2). This probe is designed to selectively react with only Fe2 separately from other metal ions and irreversibly turns into a far-red fluorescent substance. It mainly localizes inside endoplasmic reticulum (ER) and/or golgi bodies. It can also be used with a flow cytometer equipped with a red laser. FerroFarRed shows almost no cy
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