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Medchemexpress LLC Bis-PEG4-PFP ester | 1314378-12-5 | 97.0% | 250 MG
Supplier: Medchemexpress LLC 250MGHY126998
Bis-PEG4-PFP ester is a PROTAC linker that is PEG-based and can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Consists of two distinct ligands connected by a linker
- Targets an E3 ubiquitin ligase with one ligand
- Targets a specific protein with the other ligand
- Leverages the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
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