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AdipoGen Bisindolylmaleimide I HCl

Supplier: AdipoGen AGCR10110M005

Chemical. CAS 176504-36-2. Formula C25H24N4O2 . HCl. MW 412.5 . 36.5. Cell permeable kinase inhibitor with improved selectivity for protein kinase C PKC Ki = 10 nM. Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 GSK-3 inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
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