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Medchemexpress LLC Bisindolylmaleimide VIII acetate | 138516-31-1 | 99.7% | 25 MG
Supplier: Medchemexpress LLC 25MGHY129624A
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor, with an IC50 of 158 nM for rat brain PKC. It specifically inhibits various PKC isoforms including PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε. This compound facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases. It is supplied as a brown to reddish-brown solid with a molecular weight of 458.51 and chemical formula C26H26N4O4. This product is for research use only.
- Potent and selective protein kinase C (PKC) inhibitor
- Inhibits PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε isoforms
- Facilitates Fas-mediated apoptosis
- Inhibits T cell-mediated autoimmune diseases
- High purity of 99.7%
- Supplied as a solid with a brown to reddish-brown color
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