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Sigma Aldrich Fine Chemicals Biosciences Blebbistatin inhibitr 5MG
Supplier: Sigma Aldrich Fine Chemicals Biosciences B05605MG
(A)-Blebbistatin a myosin II ATPase inhibitor does not affect other members of myosin superfamily like I V and X. Blebbistatin is highly light sensitive and photobleaching can reverse its effect completely. Blebbistatin is a commonly used as excitation-contraction uncoupling agent in cardiovascular physiology. Blebbistatin controls the inhibitory effect of thrombin on intercellular Ca2 wave propagation. Blebbistatin reduces cardiac contractility by stabilizing the Off state of the thick filament.
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