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Enzo Life Sciences BML-278 (5mg). CAS: 15301-69-6
Supplier: Enzo Life Sciences BMLGR3590005
Novel Sirt activator structurally based on a dihydropyridine scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) =1μM for Sirt1 with weaker effect on Sirt2 and Sirt3 (25 and 50μM respectively). The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. Alternative name: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (5mg/ml). Long Term Storage: Ambient.
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