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Enzo Life Sciences BML-288 (25mg)

Supplier: Enzo Life Sciences BMLPD2000025

Potent (IC50=40nM) and selective (290X selectivity over other PDE isoforms) inhibitor of phosphodiesterase Type II (PDE2). Displayed no significant level of binding to neither a collection of 54 receptors and ion channels, nor to a panel of 30 kinases. BML-288 demonstrated no inhibition of 5-lipoxygenase (5-LO) or cyclooxygenase (COX-1). BML-288 is more potent and selective than EHNA (BML-PD129). Alternative name: 5-Methyl-6-oxo-N-(1,3,4-thiadiazol-2-yl)-7H-furo[2,3-f]indole-7-carboxamide. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (25 mg/ml). Long Term Storage: -20°C.
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