Medchemexpress LLC BMS-37 | 1675202-20-6 | C27H32N2O4 | 100 MG

Supplier:  Medchemexpress LLC HY150879100MG

BMS-37 is an immune checkpoint inhibitor targeting PD-1/PD-L1, with an IC50 against the PD-L1/PD-1 complex ranging from 18 to 200 nM. It demonstrates unspecific toxicity towards modified Jurkat T cells, with an EC50 between 3 and 6 μM. This compound is applicable for research into PD-L1-induced T-cell exhaustion or as a PD-L1 ligand for PROTAC molecule synthesis.

• Functions as a PD-1/PD-L1 immune checkpoint inhibitor.
• Exhibits IC50 values for the PD-L1/PD-1 complex between 18 and 200 nM.
• Displays unspecific toxicity against modified Jurkat T cells with an EC50 of 3 to 6 μM.
• Can be used for the study of PD-L1-induced exhaustion of T-cells.
• Suitable for use as a PD-L1 ligand in the synthesis of PROTAC molecules.

Catalog No. 50-003-75653