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Medchemexpress LLC BMS-37 | 1675202-20-6 | C27H32N2O4 | 25 MG
Supplier: Medchemexpress LLC 25MGHY150879
BMS-37 is a PD-1/PD-L1 immune checkpoint inhibitor with an IC50 towards the PD-L1/PD-1 complex ranging from 18 to 200 nM. It exhibits unspecific toxicity against modified Jurkat T cells with an EC50 between 3 and 6 μM. It can be utilized for studying PD-L1-induced exhaustion of T-cells or as a PD-L1 ligand for synthesizing PROTAC molecules.
- PD-1/PD-L1 immune checkpoint inhibitor.
- Can be used for the study of PD-L1-induced exhaustion of T-cells.
- Can be used as a PD-L1 ligand to synthesize PROTAC molecules.
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