Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502964146

Cayman Chemical BMS 470539hydrochlorIde 1mg
SDP

Supplier:  Cayman Chemical 222311 MG

Encompass_Preferred

An MC1R agonist; induces cAMP accumulation in B16/F10 murine melanoma cells and in CHO cells overexpressing human MC1R (EC50s = 11.6 and 16.8 nM, respectively); inhibits LPS-induced TNF-α production in mice (ED50 = 10 μmol/kg, s.c.); reduces LPS-induced leukocyte infiltration and paw swelling in mouse models of lung inflammation and delayed-type hypersensitivity, respectively; decreases retinal damage in a mouse model of streptozotocin-induced diabetic retinopathy; increases striatal dopamine levels and decreases the number of striatal α-synuclein aggregates in a mouse model of Parkinson’s disease at 20 mg/kg

Catalog No. 50-296-4146


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.