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Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY112776A

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BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. It demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase. It is intended for research use only and is not sold to patients.

  • Potent, selective, and irreversible inhibitor of CDC25 phosphatase family.
  • Inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat at micromolar concentrations.
  • Displays ~20-fold greater selectivity over CD45 tyrosine phosphatase.
  • Shown to inhibit cell proliferation in several human tumor cell lines in vitro in a concentration-dependent manner.
  • Causes cell cycle arrest at various stages.

Catalog No. 50-004-39685


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