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Medchemexpress LLC Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) | 1835705-53-7 | 99.8% | 294.81 | 50 MG
Supplier: Medchemexpress LLC HY1083711G
Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTAC technology utilizes small molecules to recruit target proteins for ubiquitination and removal by the proteasome. The synthesis of PROTAC compounds that mediate the degradation of c-ABL and BCR-ABL by recruiting either Cereblon or Von Hippel Lindau E3 ligases has been reported. It is also designated as 6-2-2.
- Used in the synthesis of PROTACs.
- PEG-based PROTAC linker.
- Utilizes small molecules to recruit target proteins for ubiquitination and removal by the proteasome.
- Mediates the degradation of c-ABL and BCR-ABL.
- Recruits Cereblon or Von Hippel Lindau E3 ligases.
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