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Medchemexpress LLC Bongkrekic acid | 11076-19-0 | 99.9% | 486.60 | 500 UG
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Supplier:  Medchemexpress LLC HY136406500UG

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Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. It is a specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid must cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport.

  • Bongkrekic acid (0-50 μM; 48 hours) stimulated formazan formation in MDA-MB-231, MCF-7, and LTED cells with EC50 of 34.14 μM, >50 μM, and 2.58 μM, respectively.
  • Bongkrekic acid (0.1-25 μM; 48 hours) decreases the living cell numbers in LTED cells and parent MCF-7 cells in a dose-dependent manner.

Catalog No. 50-003-49126


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