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Medchemexpress LLC BR-cpd7 | 98.0% | 928.82 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1637051MG

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BR-cpd7 is a PROTAC degrader designed for fibroblast growth factor receptor FGFR1/2, exhibiting a DC50 of 10 nM. This compound has been observed to arrest the cell cycle and inhibit the proliferation of tumor cells that are aberrantly activated by FGFR1/2.

  • Composed of a ligand for target protein FGFR-IN-12, a linker, and a ligand for E3 ligase Thalidomide-NH-CH2-COOH.
  • Exhibits antitumor activity.
  • Arrests cell cycle.
  • Inhibits proliferation of FGFR1/2 aberrant activated tumor cells.

Catalog No. 50-003-92523


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