Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Bractoppin | 2290527-07-8 | 99.9% | 414.47 | C25H23FN4O | 100MG
Supplier: Medchemexpress LLC HY126020100MG
Bractoppin is a small-molecule inhibitor that disrupts phosphopeptide recognition by the human BRCA1 tandem BRCT (tBRCT) domain. It preferentially inhibits BRCA1 tBRCT-dependent steps in the DNA damage response, reducing BRCA1 recruitment to DNA breaks, suppressing RAD51 assembly, and modulating damage-induced G2 arrest. In microscale thermophoresis assays it displaces a BACH1 phosphopeptide with a reported binding IC50 of 74 nM. Supplied as a high-purity research reagent for biochemical and cellular studies.
- High purity suitable for biochemical and cellular assays.
- Potent BRCA1 tBRCT inhibitor with nanomolar binding activity.
- Applicable to studies of DNA damage response and RAD51 recruitment.
- Provided as a weighed solid for solution preparation.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?