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Medchemexpress LLC Britannin | 33627-28-0 | 1 ML
Supplier: Medchemexpress LLC HYN300510MM/1ML
Britannin is an NLRP3 inhibitor demonstrating anti-inflammatory and antitumor activities. It inhibits the activation of the NLRP3 inflammasome by blocking the interaction between NLRP3 and NEK7. Additionally, Britannin exhibits antitumor properties by inhibiting tumor cell proliferation and suppressing PD-L1 expression, thereby enhancing cytotoxic T lymphocyte activity. It also induces apoptosis and autophagy in liver cancer cells through ROS-regulated AMPK activation. Britannin is a promising compound for research in anti-inflammatory and antitumor therapeutics.
- NLRP3 inhibitor
- Exhibits anti-inflammatory activity
- Inhibits activation and assembly of the NLRP3 inflammasome
- Demonstrates antitumor activity
- Induces apoptosis and autophagy in liver cancer cells
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