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Medchemexpress LLC BSJ-02-162 (CDK4/6-IN-11) | 2139329-47-6 | 98.1% | C43H49N11O7 | 10MG
Supplier: Medchemexpress LLC HY14499510MG
BSJ-02-162 (CDK4/6-IN-11) is a proteolysis-targeting chimera (PROTAC) developed for preclinical research to induce ubiquitin-mediated degradation of cyclin-dependent kinases 4 and 6. The molecule combines an E3 ligase-recruiting thalidomide-derived moiety with a palbociclib-derived target ligand connected by a modular linker to promote selective proteasomal degradation of CDK4/6.
- Induces targeted degradation of CDK4 and CDK6 via PROTAC mechanism.
- High chemical purity suitable for research applications.
- Available as a solid powder with recommended cold storage.
- Soluble in DMSO at high concentration; ultrasonic assistance may be required.
- Supplied in multiple small pack sizes for screening and optimization.
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