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Medchemexpress LLC BSP16 | 2727249-47-8 | C16H18O5Se | 500 UG
SDP

Supplier:  Medchemexpress LLC HY151264500UG

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BSP16 is a potent, orally active stimulator of interferon genes (STING) agonist. It can selectively stimulate the STING pathway and is used for cancer research.

  • Selectively stimulates the STING pathway (EC50 values of 9.24 μM in ISG-THP1 cells, 5.71 μM in ISGRAW264.7 cells).
  • Strongly activates STING signaling in human and mouse cells.
  • Promising absorption, distribution, metabolism, excretion, and toxicity profiles.
  • Well-tolerated and excellent pharmacokinetic profile in vivo.
  • Induces tumor regression and durable antitumor immunity.
  • Excellent antitumor efficacy in MC38 (colon carcinoma) syngeneic tumor model, achieving complete tumor regression.
  • Induced tumor regression in all treated mice in a CT26 (colon carcinoma) tumor model.

Catalog No. 50-003-74974


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