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Cayman Chemical Buca ntdysntca Bucntn 10mg
Supplier: Cayman Chemical 3397310 MG
A quassinoid with diverse biological activities; inhibits protein synthesis in HeLa cells, reticulocytes, and reticulocyte lysates (IC50s = 30, 40, and 1,600 nM, respectively); active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 8 and 13 nM, respectively); induces apoptosis in HL-60 leukemia and RPMI-8226 multiple myeloma cells (IC50s = 12.2 and 12.8 nM, respectively); induces tumor regression in an RPMI-8226 mouse xenograft model at 5 mg/kg
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