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Enzo Life Sciences Bufalin (10mg). CAS: 465-21-4

Supplier: Enzo Life Sciences BMLAP3030010

Cardiotonic steroid specific Na+/K+-ATPase inhibitor. More potent than ouabain (BML-CM109). Induces cell differentiation. Induces apoptosis in U937 and HL-60 cells by activation of AP-1 via a MAPK pathway that involves JNK. Regulates Tiam1 gene. Down regulates expression of 14-3-3 protein. Alternative name: (3beta,5beta)-3,14-Dihydroxybufa-20,22-dienolide, 5beta,20(22)-Bufadienolide-3beta,14-diol. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml, warm). Long Term Storage: -20°C.
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