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Medchemexpress LLC Butanamide, 3-amino-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]- | 145455-23-8 | 99.9% | 509.60 | 100 MG

Supplier: Medchemexpress LLC HY1095750MG
L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. It binds to the G protein-coupled receptor with a Ki of 63 nM and is intended for research use only.
- Growth hormone secretagogue (GHS) agonist.
- Binds to G protein-coupled receptor.
- Stimulates intracellular calcium release, inositol phosphate (IP) turnover, cAMP-responsive element binding protein (CREB) activity, serum-responsive element activity, and bioluminescence resonance energy transfer (BRET) activity with EC50 values ranging from 26 nM to 63 nM.
- Activates the MAPK pathway.
- Inhibits L-692429-stimulated GH secretion in anesthetized rats.
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