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Cayman Chemical ButenafIn13Cd3hydrochLR 10mg

Supplier: Cayman Chemical 3401010 MG

A CAIX inhibitor (Ki 0.007 UM for the recombinant human enzyme) selective for CAIX over CAI and CAII but does inhibit CAXII (Kis 5.6 0.55 and 0.002 UM respectively) inhibits proliferation of HT-29 and MDA-MB-231 but not HCT116 cancer cells under anoxic conditions (IC50s 20 481 and 1000 UM respectively) reduces the number of lung metastases but not primary tumor growth in an MDA-MB-231 mouse xenograft model at 10 mg/kg
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