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Cayman Chemical CabazItaxel 50mg
SDP

Supplier:  Cayman Chemical 2226250 MG

Encompass_Preferred

A semisynthetic taxane; stabilizes microtubule assembly by reducing lag time for tubulin assembly (LT50 = 100 nM) and the rate of cold-induced microtubule depolymerization (IC50 = 100-250 nM) in vitro; inhibits proliferation of P388, HL-60, Calc18, and KB cells (IC50s = 4-41 nM), as well as P-glycoprotein-expressing, drug-resistant versions of these cell lines (IC50s = 16-414 nM); dose-dependently reduces tumor growth in docetaxel-susceptible N87 human gastric carcinoma and docetaxel-resistant UISO BCA-1 breast cancer mouse xenograft models

Catalog No. 50-298-7897


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