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Medchemexpress LLC Calhex 231 hydrochloride | 2387505-78-2 | MFCD22580412 | 99.8% | 443.41 g/mol | C25H28Cl2N2O | 25 MG
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Supplier:  Medchemexpress LLC HY103320A25MG

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Calhex 231 hydrochloride is a selective negative allosteric modulator of the calcium-sensing receptor (CaSR) used as a research reagent to investigate CaSR-mediated signaling and related pathologies. It blocks Ca2+-induced inositol phosphate accumulation and has been applied in cellular and in vivo studies of traumatic hemorrhagic shock and diabetic cardiomyopathy.

  • Selective negative allosteric modulation of CaSR.
  • Reported IC50 ≈ 0.39 μM for human CaSR activity.
  • High chemical purity (~99.8%) suitable for research use.
  • Solid form, soluble in DMSO for biological assays.
  • Storage stability in solvent: -80°C up to 6 months, -20°C up to 1 month.

Catalog No. 50-002-44861


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