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Apexbio Technology LLC Candesartan 139481-59-7 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A59325.1
Candesartan (CAS 139481-59-7) is a small-molecule antagonist targeting the angiotensin II type 1 (AT ) receptor It is designed to selectively inhibit AT receptor-mediated vasoconstriction thereby regulating systemic vascular resistance and blood pressure Candesartan exerts its biological activity primarily through competitive antagonism of the AT receptor In in vitro studies candesartan demonstrates potent inhibition with IC values of approximately 1 12 nM in bovine adrenal cortex tissues and 2 86 nM in isolated rabbit aorta preparations Based on these pharmacological properties candesartan holds research potential in studies of cardiovascular physiology hypertension mechanisms and related therapeutic interventions
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