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Medchemexpress LLC Capromorelin (tartrate) | 193273-69-7 | C32H41N5O10 | 1 ML
Supplier: Medchemexpress LLC HY1524310MM/1ML
Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with a Ki of 7 nM for hGHS-R1a. This product stimulates growth hormone (GH) release in rat pituitary cell cultures and has shown increased food consumption and weight gain in dogs. It exhibits enhanced intestinal absorption and superior pharmacokinetic properties with high bioavailabilities in animal species.
- In vitro activity: stimulates GH release in rat pituitary cell cultures with an EC50 of 3 nM
- In vivo activity: significantly increases food consumption and weight gain in dogs
- Enhanced intestinal absorption in rodent models
- Superior pharmacokinetic properties
- High bioavailabilities in animal species: F(rat)=65% and F(dog)=44%
- Stimulates GH release in anesthetized rat models with an ED50 of 0.05 mg/kg iv
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