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Selleck Chemical LLC Carfilzomib (PR-171) 5mg 868540-17-4

Supplier: Selleck Chemical LLC S28535MG

Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the ?5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagy and induces cell apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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