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Medchemexpress LLC Cariprazine (hydrochloride) | 1083076-69-0 | 99.9% | 463.87 | 5 MG
Supplier: Medchemexpress LLC HY14763A5MG
Cariprazine hydrochloride is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
- Exhibits high affinity for D3 and D2 receptors.
- Shows moderate affinity for the 5-HT1A receptor.
- Stimulates inositol phosphate formation with high potency.
- Antagonizes human serotonin 5-HT2B receptors.
- More potent in inhibiting isoproterenol-induced cAMP production than Aripiprazole.
- Reduces striatal uptake of radioligands in vivo.
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