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ABclonal Technology Caspase-1 Rat mAb

Supplier: ABclonal Technology A2108520UL
Enables cysteine-type endopeptidase activity Involved in several processes including positive regulation of I-kappaB kinase NF-kappaB signaling positive regulation of interleukin-1 beta production and protein autoprocessing Acts upstream of or within several processes including membrane hyperpolarization mitochondrial depolarization and positive regulation of interleukin-1 alpha production Located in extracellular region Part of IPAF inflammasome complex Is expressed in knee joint and metanephros Orthologous to human CASP1 (caspase 1)
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