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Cayman Chemical Caspase6 InhIbItr Screeng 384
Supplier: Cayman Chemical 701890384 WELL
Cayman’s Caspase-6 Inhibitor Screening Assay Kit provides a robust and EAsy-to-use platform for identifying novel inhibitors of human caspase-6, a cysteine protease implicated in multiple neurodegenerative disorders. The assay uses a caspase-6-specific fluorogenic substrate, Z-VEID-AFC. Caspase-6 cleaves this substrate generating free AFC, which can be EAsily quantified using a fluorescence plate reader at excitation and emission wavelengths of 400 and 505 nm, respectively. The potent and reversible caspase-6 inhibitor Ac-VEID-CHO is included as a positive control and inhibits caspase-6 with an IC50 value of 12 nM.
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