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TARGETMOL CHEMICALS INC CAY10602 50MG
Supplier: TARGETMOL CHEMICALS INC T406250MG
Also available in 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-dependently suppresses the NF-(kappa)B-dependent induction of TNF-(alpha) by lipopolysaccharide in THP-1 cells with approximately 75% inhibition achieved at 60 uM without cytotoxicity. purity: 98%
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