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Medchemexpress LLC CC214-1 | 1021920-32-0 | C20H21N7O2 | 25 MG

Supplier: Medchemexpress LLC 25MGHY154910
CC214-1 is a potent mTOR inhibitor that induces autophagy, with an IC50 of 0.002 μM. This compound is useful as an in vitro tool for exploring mTOR kinase biology and for Glioblastoma studies.
- Potent mTOR inhibitor (IC50 of 0.002 μM)
- Induces autophagy
- Useful for exploring mTOR kinase biology in vitro
- Suitable for glioblastoma studies
- Inhibits mTORC2 (IC50 of 0.018 μM in PC-3 cells) and mTORC1 (IC50 of 0.04 μM in PC-3 cells)
- Synergizes with rapamycin to inhibit mTORC1 signaling and tumor cell proliferation
- Mediates sensitivity to growth arrest in glioblastoma cells
- Inhibits T cell activation and expression of activation markers
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